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Center for Physiology and Biophysics: News of the Day
  1. New discovery shows human cells can write RNA sequences into DNA
    In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells.

  2. How cells measure themselves
    How do cells measure themselves? Now we have an answer to this long-standing biological question.

  3. Researchers' algorithm to make CRISPR gene editing more precise
    Researchers have developed a new method which makes CRISPR gene editing more precise than conventional methods. The method selects the molecules best suited for helping the CRISPR-Cas9 protein with high-precision editing at the correct location in our DNA, the researchers explain.

  4. Ion and lipid transporters specialize for their niche
    Cell viability require that a variety of functions at the cell membrane are maintained properly. P-type ATPases translocate substrates across the membrane, and they have evolved into different types taking care of specific substrates within a diverse range. Now, key structural aspects have been described on how two different types of P-type ATPases -- a Ca2+ transporting Ca2+-ATPase and a lipid transporting P4-ATPase - have adapted to different substrates and physical environments.
    A new culprit in antibacterial resistance: Cysteine persulfide
    Scientists have developed a new, highly sensitive analytical method that can detect degraded beta-lactam antibacterial agents used in the treatment of bacterial infections. With this method, researchers found that reactive sulfur species produced by bacteria degrade and inactivate beta-lactam antibiotics.

  5. Of quirky channels and a fond farewell

    This final installment of Generally Physiological concerns F-selective channels, a surprising role for a tryptophan in determining channel identity, and a farewell note from the Executive Editor of The Journal of General Physiology.

(a) Bordetella pertussis...



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