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Center for Physiology and Biophysics: News of the Day
  1. What social stress in monkeys can tell us about human health
    A new study examines one key stress-inducing circumstance -- the effects of social hierarchy -- and how cells respond to the hormones that are released in response to that stress.

  2. New tool for understanding enzymes -- Google
    Chemistry professors used the Google algorithm PageRank to identify key amino acids in the regulation of a bacterial enzyme essential for most microorganisms.

  3. Algorithms to locate centrioles in the cell
    Investigators from the UEx have developed a methodology with new algorithms to analyze the location of the centriole in a model cell. Thanks to this technology, they have been able to discover how the actin cytoskeleton, is involved in the polarised placement of centrioles in Drosophila, just as happens in vertebrates.

  4. New light on blocking Shiga and ricin toxins -- And on an iconic biological process
    Researchers, setting their sights on Shiga toxin (player in the current E. coli outbreak from romaine lettuce) and ricin (a bioterrorism agent), have now identified potential protective strategies. Their study also sheds new light on glycosylation, the attachment of sugars to large molecules, key to cells' ability to create more diverse molecules beyond what's encoded in the genome.

  5. A code for reprogramming immune sentinels
    For the first time, a research team has successfully reprogrammed mouse and human skin cells into immune cells called dendritic cells. The process is quick and effective, representing a pioneering contribution for applying direct reprogramming for inducing immunity. Importantly, the finding opens up the possibility of developing novel dendritic cell-based immunotherapies against cancer.

  6. Of quirky channels and a fond farewell

    This final installment of Generally Physiological concerns F-selective channels, a surprising role for a tryptophan in determining channel identity, and a farewell note from the Executive Editor of The Journal of General Physiology.

(a) Bordetella pertussis...



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