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Center for Physiology and Biophysics: News of the Day
  1. Biologists trace plants' steady mitochondrial genomes to a gene found in viruses, bacteria
    Biologists have traced the stability of plant mitochondrial genomes to a particular gene - MSH1 - that plants have but animals don't. Their experiments could lend insight into why animal mitochondrial genomes tend to mutate.

  2. Discovery reveals how plants make cellulose for strength and growth
    The discovery unveils the molecular machinery that plants use to weave cellulose chains into cable-like structures called 'microfibrils.'

  3. Safer CRISPR gene editing with fewer off-target hits
    The CRISPR system is a powerful tool for the targeted editing of genomes, with significant therapeutic potential, but runs the risk of inappropriately editing ''off-target'' sites. However, a new study shows that mutating the enzyme at the heart of the CRISPR gene editing system can improve its fidelity.

  4. Structural analysis of COVID-19 spike protein provides insight into its evolution
    Researchers have characterized the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform vaccine design.

  5. New clues from fruit flies about the critical role of sex hormones in stem cell control
    In one of the first studies addressing the role of sex hormones' impact on stem cells in the gut, scientists outline new insights showing how a steroidal sex hormone, ecdysone, drastically alters the way intestinal stem cells behave, ultimately affecting the overarching structure and function of this critical organ.

  6. Of quirky channels and a fond farewell

    This final installment of Generally Physiological concerns F-selective channels, a surprising role for a tryptophan in determining channel identity, and a farewell note from the Executive Editor of The Journal of General Physiology.

(a) Bordetella pertussis...



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