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Center for Physiology and Biophysics: News of the Day
  1. Triggered by light, a novel way to switch on an enzyme
    In living cells, enzymes drive biochemical metabolic processes. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers have identified an enzyme that, when illuminated with blue light, initiates a reaction that was previously unknown in enzymatics.

  2. How a protein can inhibit cancer development in mice
    In a new study, researchers have discovered how the protein PP2A can inhibit tumor growth in mice. The protein turns off an enzyme that stimulates cell growth, thus inhibiting the development of cancer.

  3. Nanodevices show how cells change with time, by tracking from the inside
    For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

  4. Rejuvenated fibroblasts can recover the ability to contract
    A recent study has shown that rejuvenated fibroblasts can recover their ability to self-contract. This encouraging discovery holds great potential for applications in regenerative medicine and stem cell engineering.

  5. Directed protein evolution with CRISPR-Cas9
    New area of application for gene scissors: Optimized proteins for biomedical research.

  6. Of quirky channels and a fond farewell

    This final installment of Generally Physiological concerns F-selective channels, a surprising role for a tryptophan in determining channel identity, and a farewell note from the Executive Editor of The Journal of General Physiology.

(a) Bordetella pertussis...



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